Erciyes \u00dcniversitesi (ER\u00dc) M\u00fchendislik Fak\u00fcltesi G\u0131da M\u00fchendisli\u011fi B\u00f6l\u00fcm\u00fc taraf\u0131ndan yap\u0131lan \u00e7al\u0131\u015fmalarda, siyah havu\u00e7taki antosiyaninler ve \u015falgam suyundaki laktik asit bakterilerinin kolon ve karaci\u011fer kanser h\u00fccrelerini azaltt\u0131\u011f\u0131 belirlendi.<\/p>\n
ER\u00dc M\u00fchendislik Fak\u00fcltesi G\u0131da M\u00fchendisli\u011fi B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi Prof. Dr. Mahmut Do\u011fan dan\u0131\u015fmanl\u0131\u011f\u0131nda Dr. Duygu Aslan T\u00fcrker taraf\u0131ndan haz\u0131rlanan doktora tezinde, siyah havu\u00e7ta bulunan antosiyaninlerin (mor, k\u0131rm\u0131z\u0131 renk veren ve antioksidan \u00f6zellikleriyle bilinen bile\u015fikler) h\u00fccre hatlar\u0131 \u00fczerindeki etkisi incelendi.<\/p>\n
Antosiyaninlerin laboratuvar ortam\u0131nda kolon ve karaci\u011fer kanseri h\u00fccre hatlar\u0131nda, h\u00fccrelerin \u00e7o\u011falmas\u0131n\u0131 bask\u0131lay\u0131c\u0131 etkisi oldu\u011fu belirlenen \u00e7al\u0131\u015fma, 2022 y\u0131l\u0131nda “Food and Bioproducts Processing” isimli Q1 dergide makale olarak yay\u0131mland\u0131.<\/p>\n
\u00c7al\u0131\u015fman\u0131n devam\u0131 niteli\u011finde ise Dr. \u00d6\u011fr. \u00dcyesi Ahmet Yetiman’\u0131n y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcnde siyah havucun kullan\u0131ld\u0131\u011f\u0131 \u015falgam suyu \u00fczerine ara\u015ft\u0131rma yap\u0131ld\u0131.<\/p>\n
“Probiotics and Antimicrobial Proteins” dergisinde 2026 y\u0131l\u0131nda yay\u0131mlanan \u00e7al\u0131\u015fmada, \u015falgam suyundan izole edilen baz\u0131 laktik asit bakterilerin laboratuvar ko\u015fullar\u0131nda antioksidan aktivite g\u00f6sterdi\u011fi, kolesterol\u00fc ortamdan uzakla\u015ft\u0131rd\u0131\u011f\u0131, ince ve kal\u0131n ba\u011f\u0131rsak kanseri h\u00fccrelerinde h\u00fccre \u00e7o\u011falmas\u0131n\u0131 azalt\u0131c\u0131 etki g\u00f6sterdi\u011fi tespit edildi.<\/p>\n
Prof. Dr. Mahmut Do\u011fan, AA muhabirine, g\u0131da kimyas\u0131 \u00e7er\u00e7evesinde \u00f6zellikle meyve ve sebzelerin at\u0131klar\u0131ndan katma de\u011feri y\u00fcksek bile\u015fikler \u00fcretmeyi hedeflediklerini s\u00f6yledi.<\/p>\n
Bu kapsamda pektin, sel\u00fcloz, karboksimetil sel\u00fcloz (sel\u00fclozdan elde edilen, suda kolayca \u00e7\u00f6z\u00fcnebilen yar\u0131 sentetik bir polimer) gibi katma de\u011fer sa\u011flayacak \u00fcr\u00fcnleri bu at\u0131k maddelerden \u00fcrettiklerini anlatan Do\u011fan, bunlar\u0131n hepsini y\u00fcksek lisans veya doktora tezi olarak haz\u0131rlad\u0131klar\u0131n\u0131 dile getirdi.<\/p>\n
Do\u011fan, siyah ve turuncu havu\u00e7tan renk maddesi \u00fcretilmesi y\u00f6n\u00fcnde bir proje haz\u0131rlad\u0131klar\u0131n\u0131 ve doktora tezi olarak yay\u0131mlad\u0131klar\u0131n\u0131 ifade ederek, renk maddesini \u00fcrettikten sonra kalite parametrelerini incelediklerini kaydetti.<\/p>\n
– Siyah havu\u00e7taki renk maddesinin antikanser etkisi tespit edildi<\/p>\n
Bu maddenin biyoaktif \u00f6zelliklerini ara\u015ft\u0131rd\u0131klar\u0131n\u0131 ve \u00e7al\u0131\u015fmalar\u0131n\u0131 kanser \u00fczerine y\u00f6nlendirdiklerini dile getiren Do\u011fan, antosiyaninler ad\u0131 verilen renk maddelerinin karaci\u011fer ve kolon kanseri h\u00fccrelerindeki etkilerini de\u011ferlendirdiklerini belirtti.<\/p>\n
Hacettepe \u00dcniversitesi ile i\u015fbirli\u011fi yapt\u0131klar\u0131n\u0131 anlatan Do\u011fan, “Neticede siyah havu\u00e7taki renk maddesinin, kolon kanseri h\u00fccresine olumlu etkisinin oldu\u011funu g\u00f6zlemledik. Antikanser etkisinin oldu\u011funu g\u00f6rd\u00fck. Yine karaci\u011fer h\u00fccre k\u00fclt\u00fcrlerinde de olumlu etkilerini tespit ettik. Bu bulgular\u0131 yay\u0131na d\u00f6n\u00fc\u015ft\u00fcrd\u00fck. Uluslararas\u0131 \u00e7apta \u00f6nemli dergilerde birka\u00e7 yay\u0131n yapt\u0131k. En iyi dergilerde bu sonu\u00e7lar\u0131 yay\u0131nlam\u0131\u015f olduk.” dedi.<\/p>\n
Do\u011fan, bu sonu\u00e7lar\u0131n ard\u0131ndan Ahmet Yetiman ile siyah havucun kullan\u0131ld\u0131\u011f\u0131 \u015falgam suyu \u00fczerinde \u00e7al\u0131\u015ft\u0131klar\u0131n\u0131, \u015falgam suyunun i\u00e7indeki 50-55 t\u00fcr laktik asit bakterisini izole ettiklerini anlatt\u0131.<\/p>\n
Bu bakterilerin antioksidan ve di\u011fer fonksiyonel \u00f6zelliklerini ele alarak bir se\u00e7im yapt\u0131klar\u0131n\u0131 dile getiren Do\u011fan, Lactobacillus brevis (fermente g\u0131dalarda ve insan mikrobiyotas\u0131nda bulunan, \u00e7ubuk \u015feklinde, gram-pozitif ve laktik asit \u00fcreten bir bakteri t\u00fcr\u00fc) bakterisinin kolon kanseri h\u00fccre k\u00fclt\u00fcr\u00fc \u00fczerindeki etkisini denediklerini s\u00f6yledi.<\/p>\n
Proje i\u00e7in K\u0131r\u015fehir Ahi Evran \u00dcniversitesi T\u0131p Fak\u00fcltesi \u0130mm\u00fcnoloji B\u00f6l\u00fcm\u00fc ile i\u015fbirli\u011fi yapt\u0131klar\u0131n\u0131 belirten Do\u011fan, “H\u00fccre k\u00fclt\u00fcr\u00fc \u00e7al\u0131\u015fmalar\u0131n\u0131 orada y\u00fcr\u00fctt\u00fck. Bu \u00e7al\u0131\u015fman\u0131n sonucunda elde edilen bakterinin hem ince ba\u011f\u0131rsak hem de kal\u0131n ba\u011f\u0131rsak kanser h\u00fccrelerinde y\u00fczde 90-95 d\u00fczeyinde h\u00fccreleri bozdu\u011funu, azaltt\u0131\u011f\u0131n\u0131 tespit ettik. Bu bakterinin kendisi veya di\u011fer laktik asit bakterileri \u015falgam\u0131n i\u00e7erisinde bulunuyor.” diye konu\u015ftu.<\/p>\n
\u00dcniversiteden \u00e7\u0131kan bilimsel \u00e7al\u0131\u015fmalar\u0131n ya ekonomiye ya da insan sa\u011fl\u0131\u011f\u0131na katk\u0131s\u0131n\u0131n olaca\u011f\u0131n\u0131 vurgulayan Do\u011fan, “Gen\u00e7lerimiz, orta ya\u015f kesim daha \u00e7ok gazl\u0131 i\u00e7ecekleri tercih ediyorlar. Halbuki bu \u015fekilde fonksiyonel \u00f6zelli\u011fi y\u00fcksek, sa\u011fl\u0131\u011fa ciddi \u015fekilde etkisi bulunan \u015falgam\u0131n, ayran\u0131n t\u00fcketilmesinin \u00f6nemli oldu\u011funu vurguluyoruz.” ifadesini kulland\u0131.<\/p>\n
Do\u011fan, t\u0131p ya da eczac\u0131l\u0131k fak\u00fcltelerinin bu \u00e7\u0131kt\u0131lardan yararlanarak kanser hastalar\u0131nda veya deneysel hayvan modellerinde bunlar\u0131 \u00e7al\u0131\u015fabileceklerini s\u00f6zlerine ekledi.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"
Erciyes \u00dcniversitesi (ER\u00dc) M\u00fchendislik Fak\u00fcltesi G\u0131da M\u00fchendisli\u011fi B\u00f6l\u00fcm\u00fc taraf\u0131ndan yap\u0131lan \u00e7al\u0131\u015fmalarda, siyah havu\u00e7taki antosiyaninler ve \u015falgam suyundaki laktik asit bakterilerinin kolon ve karaci\u011fer kanser h\u00fccrelerini azaltt\u0131\u011f\u0131 belirlendi. ER\u00dc M\u00fchendislik Fak\u00fcltesi G\u0131da M\u00fchendisli\u011fi B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi Prof. Dr. Mahmut Do\u011fan dan\u0131\u015fmanl\u0131\u011f\u0131nda Dr. Duygu Aslan T\u00fcrker taraf\u0131ndan haz\u0131rlanan doktora tezinde, siyah havu\u00e7ta bulunan antosiyaninlerin (mor, k\u0131rm\u0131z\u0131 renk …<\/p>\n","protected":false},"author":1,"featured_media":152751,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[49067,49065,3823,1773,49063,49066,25208,8931,11363,9490,49064],"class_list":["post-152750","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-turkiye","tag-azalttigi","tag-bakterinin","tag-belirlendi","tag-edilen","tag-havuclu","tag-hucrelerini","tag-izole","tag-kanser","tag-salgam","tag-siyah","tag-suyundan"],"_links":{"self":[{"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/posts\/152750"}],"collection":[{"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/comments?post=152750"}],"version-history":[{"count":0,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/posts\/152750\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/media\/152751"}],"wp:attachment":[{"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/media?parent=152750"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/categories?post=152750"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kibrishost.com\/tak\/wp-json\/wp\/v2\/tags?post=152750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}